Smuggler I
Smuggler II
Milo Smutts

Gender: ♂

Main
X-Men Unlimited (I) 41

Alistaire Alphonso Smythe
Snake Marston
Snapdragon

Sheoke Sanada
Gender: ♀

Features
Captain America: America's Avenger 1.FT

Snarks
Sneepers
Snigger
Snippy
Charles Snow

Gender: ♂
Member of: Daily Bugle Staff

Snow Leopards

Member of: Remont Six

Snow Queen
Snowbird
Snowblind
S.O.D.A.M.

Olinka Barankova (Specialized Organism Designed for Agressive Maneuvers)
Gender: ♀
Alias of: M.O.D.A.M.

Dr. Karla Sofen
Solarr
Soldier Supreme
Soldiers of the Serpent

Universe/Dimension/Timeline: Earth M2 (Earth-982)

Features
Spider-Girl (I) 100.FT

Solitaire
Solo I
Solo II
Solons
Solution

Universe/Dimension/Timeline: Malibu Universe

Main
Ultraverse Origins (Malibu Comics) 1

Son of Satan
Son of Satan (GoldAge)

Gender: ♂
Parent(s): Loki

Features
Thor: Asgard's Avenger 1.FT

Erica Sondheim

Gender: ♀

Features
Iron Manual Mark 3 1.FT

Songbird
Sons of the Serpent
Sons of the Tiger
Sons of the Tiger (HouseOfM)
Sons of Yinsen
Sorcerer I
Sorcerer II
Sorceress

Gender: ♀
Alternate version of: Sersi
Member of: Morgana Le Fey's Alternate Avengers

Dr. Henri Sorel

Gender: ♂

Sorrow
Bobby Soul

Gender: ♂

Features
Heroic Age: X-Men 1.FT

Soul Gem
Soul-Eater
Soulsword
Candance Southern
Southpaw
Sovel Redhand

Gender: ♂
Individual of: Shi'ar

Features
Heroic Age: Villains 1.FT

Soviet Super-Soldiers
Space Gem

(Purple)
Member of: Infinity Gems
Owned by: Pip the Troll

Space Parasite
Space Phantom
Space Phantoms
Space Rangers
Spaceknights I
Spaceknights II
Spacemen
Hope Spalding-Summers